Measuring surface water quality using a low-cost sensor kit within the context of rural Africa

Monitoring water quality is done for a variety of reasons, including to determine whether water is suitable for drinking or agricultural purposes. In rural areas of Africa the traditional way of measuring water quality can be costly and time consuming. In this research, we have developed a low-cost water quality measuring device that designed to operate in the context of rural Africa. Firstly we select appropriate water quality sensors. Secondly we developed a water quality monitoring device that takes the contextual requirements and constraints of rural Africa into account. Lastly the device is evaluated and tested using water samples that were collected in rural Africa

Relations among basic psychological needs, PE-motivation and fundamental movement skills in 9–12-year-old boys and girls in Physical Education

: Many children aged 9–12 appear to have low levels of fundamental movement skills (FMS). Physical education (PE) is important because PE-teachers can teach children a variety of FMS and can influence PE-motivation. However, declined levels of PE-motivation are reported in the final grades of elementary school. Therefore, more insight in the relations between PE-motivation and FMS is needed. Purposes: In the first phase, instruments to measure the satisfaction of basic psychological needs (competence, autonomy, classmate relatedness and teacher relatedness) and PE-motivation (autonomous and controlled) in 9–12-year-old children were developed and validated. The purpose of the second phase was to examine the influence of basic psychological needs on PE-motivation, the influence of PE-motivation on locomotor skills, object control skills and balance skills, and the direct influence of basic psychological needs on FMS for boys and girls aged 9–12. Participants and data collection: In the first phase, 172 children (82 boys, 90 girls, M = 10.72 years ± 0.77) filled out questionnaires assessing the satisfaction of their basic psychological needs and motivation for PE. Forty-eight children completed the questionnaires again 4 weeks later. In the second phase, a total of 138 children (66 boys, 72 girls, 10.8 years ± .79) (three schools from phase 1 and one new school) participated. Children from the new school also completed the questionnaires and all children conducted the subtest for speed and agility, upper limb coordination and balance of the Bruininks-Oseretsky Test of Motor Proficiency 2. Data analysis: In phase 1, linear weighted Kappa's and the Mokken Scale Program for polychotomous items were used to test reliability and validity. In phase 2, Pearson's correlations and multiple linear regression analyses were performed to examine the relations. Findings: Regarding phase 1, all subscales were reliable and the validity was considered moderate to strong except for the autonomy subscale, which was not reliable and valid. With respect to phase 2, all basic psychological needs, except autonomy among girls, had moderate to strong correlations with autonomous PE-motivation. Teacher relatedness was the most important predictor for boys and girls, while the second predictor was classmate relatedness for boys and competence for girls. No positive significant relations between basic psychological needs and FMS and between PE-motivation and FMS were found. In contrary, moderate but negative relations between teacher relatedness and balance skills and between autonomous PE-motivation and balance skills were found for boys. Conclusions: The results confirmed the importance of the basic psychological needs in the prediction of autonomous PE-motivation in 9–12-year-old children. Although all needs should be supported by the PE-teacher, it is important to be aware of the different impact of the needs on autonomous PE-motivation for boys and girls. Despite the missing relations with FMS, PE-teachers seem to be able to autonomously motivate children for PE regardless of their FMS proficiency

Motivational Principles and Personalisation Needs for Geo-Crowdsourced Intangible Cultural Heritage Mobile Applications

Whether it’s for altruistic reasons, personal gains, or third party’s interests, users are influenced by different kinds of motivations when making use of mobile geo-crowdsourcing applications (geoCAs). These reasons, extrinsic and/or intrinsic, must be factored in when evaluating the use intention of these applications and how effective they are. A functional geoCA, particularly if designed for Volunteered Geographic Information (VGI), is the one that persuades and engages its users, by accounting for their diversity of needs across a period of time. This paper explores a number of proven and novel motivational factors destined for the preservation and collection of Intangible Cultural Heritage (ICH) through geoCAs. By providing an overview of personalisation research and digital behaviour interventions for geo-crowdsoured ICH, the paper examines the most relevant usability and trigger factors for different crowd users, supported by a range of technology-based principles. In addition, we present the case of StoryBee, a mobile geoCA designed for “crafting stories” by collecting and sharing users’ generated content based on their location and favourite places. We conclude with an open-ended discussion about the ongoing challenges and opportunities arising from the deployment of geoCAs for ICH

mTor inhibitor GDC-0349 improves ASO induced SAMMSON knock down resulting in enhanced anti-tumor efficacy in uveal melanoma

Uveal melanoma (UM) is the most common intraocular malignancy in adults. The lack of an effective treatment results in a median survival time of less than one year for patients with metastatic disease and shows the high unmet need for the development of effective treatments. Recently, the melanoma-specific lncRNA SAMMSON was shown to be essential for skin melanoma survival. Analysis of a PAN cancer RNA-sequencing dataset revealed consistent expression of SAMMSON in uveal melanoma tumors. Targeting SAMMSON by means of antisense oligonucleotides (ASOs) results in a strong reduction in cell viability with induction of apoptosis of UM cells and slows down tumor growth in multiple UM PDX models. These effects were driven by impaired mitochondrial function and protein translation, resulting in cell death. To identify potential synergistic combinations, we combined SAMMSON knockdown with a library of 2911 FDA-approved drugs and quantified cell viability in a uveal melanoma cell line. The strongest synergy was obtained with the mTOR inhibitor GDC-0349. Combining SAMMSON knockdown with mTOR inhibition resulted in enhanced impairment of mitochondrial function and protein synthesis. Interestingly, we observed a more pronounced knockdown of SAMMSON when combining SAMMSON targeting ASOs with GDC-0349, suggesting mTOR inhibition facilitates ASO uptake in uveal melanoma cells. Further experiments are ongoing to confirm this mechanism. Taken together, these results demonstrate that SAMMSON inhibition in combination with mTOR inhibition could be a novel treatment option for uveal melanoma patients

Measuring surface water quality using a low-cost sensor kit within the context of rural Africa

Monitoring water quality is done for a variety of reasons, including to determine whether water is suitable for drinking or agricultural purposes. In rural areas of Africa the traditional way of measuring water quality can be costly and time consuming. In this research, we have developed a low-cost water quality measuring device that designed to operate in the context of rural Africa. Firstly we select appropriate water quality sensors. Secondly we developed a water quality monitoring device that takes the contextual requirements and constraints of rural Africa into account. Lastly the device is evaluated and tested using water samples that were collected in rural Africa

Exploring West African folk narrative texts using machine learning

This paper examines how machine learning (ML) and natural language processing (NLP) can be used to identify, analyze, and generate West African folk tales. Two corpora of West African and Western European folk tales are compiled and used in three experiments on cross-cultural folk tale analysis. In the text generation experiment, two types of deep learning text generators are built and trained on the West African corpus. We show that although the texts range between semantic and syntactic coherence, each of them contains West African features. The second experiment further examines the distinction between the West African and Western European folk tales by comparing the performance of an LSTM (acc. 0.74) with a BoW classifier (acc. 0.93), indicating that the two corpora can be clearly distinguished in terms of vocabulary. An interactive t-SNE visualization of a hybrid classifier (acc. 0.85) highlights the culture-specific words for both. The third experiment describes an ML analysis of narrative structures. Classifiers trained on parts of folk tales according to the three-act structure are quite capable of distinguishing these parts (acc. 0.78). Common n-grams extracted from these parts not only underline cross-cultural distinctions in narrative structures, but also show the overlap between verbal and written West African narratives

distributed intelligent system

In this work we present a framework for multi-agent system design which is based both on human organizational notions and principles for distributed intelligent systems design. The framework elaborates on the idea that notions from the field of organizational design can be used as the basis for the design of distributed intelligent systems. Concepts such as task, control, job, operation, management, coordination and organization are framed into an agent organizational framework. A collection of organizational design activities is presented that assist in a task oriented decomposition of the overall task of a system into jobs and the reintegration of jobs using job allocation, coordination mechanisms and organizational structuring. A number of coordination mechanisms have been defined in the organizational design literature. For the scope of this work we concentrate on: Direct Supervision where one individual takes all decisions about the work of others, Mutual Adjustment that achieves coordination by a process of informal communication between agents, and Standardization of Work, Output and Skills. Three organizational structures are discussed, that coordinate agents and their work: Machine Bureaucracy, Professional Bureaucracy and Adhocracy. The Machine Bureaucracy is task-driven, seeing the organization as a single-purpose structure, which onl